Insightec

Startup
FUNDED
Focused ultrasound medical treatments
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$14,676,169
invested through OurCrowd in
3 previous rounds.
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Overview: Insightec

Insightec is the first company to develop and commercialize a technology that successfully, and without incision, targets and inserts ultrasound waves through the skull. Utilizing magnetic resonance-guided focused ultrasound, the company currently offers technology for incisionless brain surgery to treat essential tremor and tremor-dominant Parkinson's Disease. In addition to these FDA approvals, the technology is currently in clinical trials for treating a number of other conditions.

The details here are based on public information, and verified solely by the company.
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Co Investors

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Insightec Management Team

Maurice FERRÉ, MD

CEO and Chairman of Board

Maurice R. Ferré MD is INSIGHTEC’S CEO and Chairman of the Board of Directors. Dr. Ferré brings over 20 years of experience in the medical device industry. Before INSIGHTEC, Dr. Ferré served as Chairman of the Board and CEO of MAKO Surgical Corp, a transformational robotic surgical company that he co-founded in 2004. The company was IPO’d in 2008 and recently sold to Stryker Corp. for $1.65 billion in 2013. Prior to MAKO, Dr. Ferré was Founder, CEO and President of Visualization Technology Inc. (1993-2002). VTI became the world leader in image guided surgery for ENT, cranial and orthopedic procedures. The Company was acquired by GE Healthcare in 2002. Dr. Ferré received his Doctor of Medicine and Master of Public Health from Boston University in 1992. He was also the recipient of the prestigious Ernest & Young 2007 Entrepreneur of the Year Award. Dr Ferre is currently active on the following boards: Advamed, The Everglades Foundation and Boston University.

Kobi Vortman, PHD

Founder and Vice Chairman of the Board

Jacob “Kobi” Vortman is INSIGHTEC’s Vice Chairman of the Board. Kobi founded the company in 1999 and under his leadership, INSIGHTEC has been developing and marketing its Magnetic Resonance guided Focused Ultrasound (MRgFUS) technology. Prior to founding INSIGHTEC, Kobi served as President of Elbit Medical Imaging where he was responsible for the development of the proprietary MRgFUS technology that was passed to INSIGHTEC when it was established as a joint effort with Elbit Medical Imaging and GE Healthcare (formerly GE Medical Systems). GE Healthcare remains a major shareholder of the company until today. Previously Kobi served as President and Chief Executive Officer at Diasonics Vingmed Ultrasound and as General Manager at ElscinTEC. Twenty years prior, he worked with RAFAEL, holding many positions, including marketing, business development, operations and engineering roles. Kobi Vortman received his PhD in Electro Optics and a BSc in Electrical Engineering from the Technion, Israel Institute of Technology in Haifa. He also received a BSc in Physics and Mathematics from the Hebrew University of Jerusalem.

Eyal Zadicario‚ PHD

Chief Operating Officer and General Manager

Eyal manages all activities in Israel and is a member of the executive management team. Eyal has been involved in research and development of multidisciplinary technology projects for more than 25 years. Eyal joined INSIGHTEC in 1999 and has held various positions in the R&D team, including software development, project leadership and product management positions. In 2001, Eyal was appointed to be INSIGHTEC’s Neuro Program Manager. In 2011, he was appointed VP of R&D, leading the company’s technology and innovation. Eyal holds a PhD in Computer Science from Tel Aviv University’s School of Mathematics and a BsC in Aeronautical Engineering (Cum Laude) from the Technion, Israel Institute of Technology.

Nadir Alikacem, PHD

VP of Global Regulatory Affairs and CRO

Nadir Alikacem is INSIGHTEC’s Vice President of Global Regulatory Affairs and CRO. He is responsible for regulatory strategy, clinical research planning, research protocol coordination, working with all relevant regulatory bodies and managing the CRO activities. Prior to joining INSIGHTEC, Nadir was an Assistant Professor at UT southwestern Medical Center in Dallas, Texas. Previously, he was a Scientist at Saint Francois’ D’Assise Hospital in Quebec-City, Canada. Nadir Alikacem received his Postdoctoral fellowship in Physics from the University of Massachusetts at Amherst, Massachusetts. He received a PhD & MSc in Physics from the University of Sussex, England.

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At a Glance: Insightec

Insightec’s mission is to help transform lives by delivering the therapeutic power of focused ultrasound. The company strives to turn dependence into independence; discouragement into joy. Today, Insightec offers safe and effective treatments for serious neurologic diseases such as tremor associated with Essential Tremor and Parkinson’s Disease and continues to collaborate, innovate and evaluate its platform for a wide range of diseases.

Insightec Products

Insightec has developed two Focused Ultrasound platforms, Exablate Neuro and Exablate Body. Both are protected by a wide array of patents.

 

The products use focused ultrasound, or sound waves, to precisely target tissue to be ablated. The treating physician controls the system from an MRI control room, using a mouse instead of a scalpel to perform the procedure. When high intensity, ultrasound waves are converged, they heat and ablate targeted tissue inside the body, without making any incisions

 

MRI imaging provides high resolution anatomical imaging for patient-specific treatment planning, as well as real-time temperature monitoring of the target and adjacent tissue.

 

Exablate Neuro is used to treat tremor associated with Essential Tremor and Parkinson’s Disease. The location of the treatment can be controlled with sub millimeter accuracy, while the size of the lesion is controlled to within 2-5 mm.

 

The Exablate Body platform is used for ablation of tissue in the prostate and symptomatic uterine fibroids and for pain palliation of bone metastases.

 

Regulatory and Insurance Approvals

Exablate Neuro is FDA approved for both Essential Tremor and Parkinson’s Disease. Treatment for Essential Tremor is approved by Medicare and many private insurers across the U.S. The company also has regulatory and reimbursement approval in many countries throughout the world.

 

Exablate Body is approved and reimbursed for various indications in different countries around the world, but it is currently not the company's focal point of commercialization.

Insightec Partners

Insightec partners with GE Healthcare, Siemens Healthineers, and Royal Philips to MRI compatibility. Currently, Insightec is commercially approved for compatibility with GE and Siemens MRIs. 

Treatment Centers

Treatment centers using Insightec’s Focused Ultrasound can be found on five continents around the globe.

Leadership

CEO Maurice R. Ferre, MD, previously led MAKO Surgical Corp., a transformational robotic surgery company he founded, to a $1.65 billion acquisition. Prior to that he led Visualization Technology Inc., the world leader in image-guided surgery, to an acquisition by GE Healthcare. 


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