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Virtual reality sports offer a novel and effective strategy to reduce fat mass and holistically promote metabolic, physical, psychological and cognitive health in adolescents with excess body weight, yielding similar, and at times superior, benefits compared with conventional real-world sports.
Greater diversity of dietary flavonoid intake correlated with reduced all-cause mortality risk and chronic disease incidence among UK Biobank participants.
A reinforcement learning-based virtual reality system, implementing a series of sport sessions with coaching, was as effective as standard physical activity in reducing fat mass in adolescents, with positive effects on cognition.
Analysis of national survey data reveals large declines in self-reported mental well-being among female parents, which suggests that maternal mental health should be a focal point of public health efforts.
A focus on implementation for non-communicable diseases could help to deliver a 50% reduction in the probability of premature mortality worldwide by 2050.
In a cluster-randomized trial conducted across 70 medical centers in six countries, a 16-week structured educational program for healthcare providers improved adherence to guidelines for rhythm control but not for stroke prevention in individuals with atrial fibrillation.
Insights into TB heterogeneity are informing strategies for patient stratification and treatment shortening; this Perspective discusses the formidable challenge of treating this complex disease with strategies that can be implemented across global settings, for effective disease control.
In the 12-week, phase 2a DUET study, treatment with TERN-501, a thyroid hormone receptor β agonist, as monotherapy or in combination with TERN-101, a farnesoid X receptor agonist, resulted in dose-dependent reductions in liver fat content as compared to placebo in patients with presumed metabolic dysfunction-associated steatohepatitis.
Interrogation of electronic health records and the B and T cell repertoires of people with PSC shows a link between Epstein–Barr virus and primary sclerosing cholangitis, an incurable autoimmune liver disease.
